Over-the-counter Phentermine alternatives put less of a strain on your body than Phentermine does. They’re less likely to cause drug interactions or side effects of Phentermine long term usage. Because they’re less powerful, these herbal OTC alternative supplements can be used for longer than prescription-strength Phentermine drug. However, at this time, no over-the-counter phentermine alternatives are proven to work. If you're looking to keep your hunger in check while on a reduced-calorie diet, try some practical and easy-to-implement dietary strategies that have staying power. Bottom line – Over-the-counter phentermine is not the same as the prescription drug, but may mimic some of the effects of the prescription-only drug. Purchasing real phen without a prescription is illegal in the United States. Prescription drugs, like diethylpropion and orlistat, and over-the-counter medications like Phentermin-D™ and phentranine, are drug therapies that can all be used as an alternative to phentermine to aid in weight loss. Over-the-counter diet pills are advertised with frequency on TV, enticing viewers to buy these products as a way to easy weight loss. Many of these products make unsubstantiated claims, however. There is only one OTC diet pill, orlistat, that is approved by the U.S. Food and Drug Administration for Phentermine Alternatives – Top Best Herbal Diet Pills Like Phentermine Drug. What is the best over the counter weight loss pill similar to Phentermine medicines? I just researched this, and from I see, you can purchase phentermine over the counter. I think what is not available now is phen/phen, which had two properties in it. Please be careful though, and I would suggest going to a diet doctor to be monitored if you choose to go that route. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Sisto on adipex over the counter equivalent: the same active ingredient, but some people respond differently to different brands. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using. See also: Phentermine drug interactions (in more detail) Further information. Remember, keep this and all other medicines out of the reach of children, never share. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Majeroni on is there a good over the counter alternative to adipex: There are no effective over-the -counter appetite suppressant, orlistat (alli) can be helpful in weight loss by cutting down on the fat you absorb, but it is essential to follow a low fat diet..